The prusa printer is great and works really well as long as you take care of it throughout the year. Prusa has a lot of documentation online as well as Q&A blogs, so if there is anything wrong with this printer you will for sure find a solution online very easily.
The two main calibrations you will have to do are the XYZ Calibration and the First Layer Calibration.
The printer takes you through the calibration step by step on the LCD screen so it is very easy to do. If there is any issue during the calibration, you can have a look at the documentation online to fix it. And as I said before, their documentation is really good so you'll have all the information you need to successfully calibrate everything.
The XYZ Calibration only needs to be done if you've taken apart the bed and/or the E-axis of the printer (the printer always lets you know when you have to do it anyways). The First Layer Calibration always needs to be done after a XYZ Calibration, but also if the print is not sticking to the bed sheet. Make sure you follow the advices on here to calibrate the first layer properly.
We used PrusaSlicer to slice the files for the prusa printer. It works very well and is easy to use. You need to import STL files in the slicer to be able to slice the part you design in solidworks, so make sure you save your solidworks files as STL files if you want to print them.
If anything needs to be fixed, there is a lot of documentation which will for sure help you find an easy way to fix the printer. They have step by step guides on how to replace any part on the printer, as well as tests to do to figure out exactly which part is causing the issue. And if you cannot find it in their documentation, there are many Q&A blogs which will let you know how to fix the issue you're having with the printer.